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Hyzaar (combination of hydrochlorothiazide and losartan) is a prescription medicine than can be used to treat high blood pressure and reduce the risk of a stroke. It works by preventing your body from absorbing too much salt and keeping the blood vessels from narrowing. Do not start taking this drug if you are allergic to its active ingredients or are unable to urinate. Hyzaar has been reported to cause harm to unborn babies if taken by pregnant women during the second and third trimesters of pregnancy. Avoid getting pregnant during the whole period of treatment and use reliable methods of birth control. Try not to get dehydrated or overheated when exercising or in hot weather. Certain health conditions can interfere with your treatment or cause complications. Make sure you let your doctor know about one of the following health conditions: liver disease, kidney disease, lupus, gout, diabetes, allergy to sulfa drugs, low or high levels of potassium in your blood, congestive heart failure, asthma or allergies. Hyzaar is FDA pregnancy category D, which means it can cause harm to an unborn baby and even lead to its death. It is unknown whether this medicine can pass into breast milk. Do not start taking it before talking to your doctor if you are pregnant or breastfeeding.